Selected Publications

Early Lung Disease Exhibits Bacteria-Dependent and -Independent Abnormalities in Cystic Fibrosis Pigs. Bouzek DC, Abou Alaiwa MH, Adam RJ, Pezzulo AA, Reznikov LR, Cook DP, Aguilar Pescozo MI, Ten Eyck P, Wu C, Gross TJ, Hornick DB, Hoffman EA, Meyerholz DK, Stoltz DA. Am J Respir Crit Care Med. 2021 Sep 15;204(6):692-702. doi: 10.1164/rccm.202102-0451OC.PMID: 34170795

Early pathogenesis of cystic fibrosis gallbladder disease in a porcine model. Zarei K, Stroik MR, Gansemer ND, Thurman AL, Ostedgaard LS, Ernst SE, Thornell IM, Powers LS, Pezzulo AA, Meyerholz DK, Stoltz DA. Lab Invest. 2020 Nov;100(11):1388-1399. doi: 10.1038/s41374-020-0474-8. Epub 2020 Jul 27.PMID: 32719544 

Mucociliary Transport in Healthy and Cystic Fibrosis Pig Airways. Xie Y, Ostedgaard L, Abou Alaiwa MH, Lu L, Fischer AJ, Stoltz DA. Ann Am Thorac Soc. 2018 Nov;15(Suppl 3):S171-S176. doi: 10.1513/AnnalsATS.201805-308AW.PMID: 30431346

CF airway smooth muscle transcriptome reveals a role for PYK2. Cook DP, Adam RJ, Zarei K, Deonovic B, Stroik MR, Gansemer ND, Meyerholz DK, Au KF, Stoltz DA. JCI Insight. 2017 Sep 7;2(17):e95332. doi: 10.1172/jci.insight.95332. eCollection 2017 Sep 7.PMID: 28878137 

Postnatal airway growth in cystic fibrosis piglets. Adam RJ, Abou Alaiwa MH, Bouzek DC, Cook DP, Gansemer ND, Taft PJ, Powers LS, Stroik MR, Hoegger MJ, McMenimen JD, Hoffman EA, Zabner J, Welsh MJ, Meyerholz DK, Stoltz DA. J Appl Physiol (1985). 2017 Sep 1;123(3):526-533. doi: 10.1152/japplphysiol.00263.2017. Epub 2017 Jun 15.

Acute administration of ivacaftor to people with cystic fibrosis and a G551D-CFTR mutation reveals smooth muscle abnormalities. Adam RJ, Hisert KB, Dodd JD, Grogan B, Launspach JL, Barnes JK, Gallagher CG, Sieren JP, Gross TJ, Fischer AJ, Cavanaugh JE, Hoffman EA, Singh PK, Welsh MJ, McKone EF, Stoltz DA. JCI Insight. 2016 Apr 7;1(4):e86183. doi: 10.1172/jci.insight.86183.PMID: 27158673 

Origins of cystic fibrosis lung disease. Stoltz DA, Meyerholz DK, Welsh MJ.
N Engl J Med. 2015 Apr 16;372(16):1574-5. doi:  10.1056/NEJMc1502191.PMID: 25875271